| 6 matches found in 3 documents. Search time: 0.093 seconds. |
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Score: 4.00 |
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| Title: Kochujang , a Korean fermented red pepper plus soybean paste , improves glucose homeostasis in 90% pancreatectomized diabetic rats .
| | Author: Kwon DY Hong SM Ahn IS Kim YS Shin DW Park S | | Journal: Nutrition Citation: V : P : Year: 2009 Type: Publisher | | Literature: oryza Field: abstract Doc ID: pub19251395 Accession (PMID): 19251395 | | Abstract: OBJECTIVES : Red pepper and soybeans have been reported to modulate energy and glucose metabolism .
However , the antidiabetic effect of kochujang , the fermented product of red pepper plus soybeans , has not been studied .
We examined whether kochujang affected insulin secretion from beta-cells and/or peripheral insulin resistance in 90% pancreatectomized diabetic rats fed high-fat diets .
METHODS : Diabetic rats consumed a high-fat diet containing two different kinds of 5% kochujang powder or the equivalent amount of nutrients for 8 wk .
Two types of kochujang were made through the fermentation of two different kinds of meju ( soybeans ) , red peppers , glutinous rice , and malts .
Meju was produced by fermenting soybeans in a traditional method ( TMK ) or in a more modern method in which soybeans are inoculated with Bacillus subtilus and Aspergillus sojae ( MMK ) .
RESULTS : TMK and MMK decreased body weight , visceral fat , and serum leptin levels without modulating caloric intake in diabetic rats compared with the control .
TMK and MMK also improved glucose tolerance by enhancing insulin sensitivity but did not potentiate glucose-stimulated insulin secretion .
The improvement in hepatic insulin sensitivity caused by TMK and MMK was explained by the potentiated phosphorylation of signal transducer and activator of transcription-3 --> adenosine monophosphate kinase --> acetyl-coenzyme A carboxylase and decreased phosphoenolpyruvate carboxykinase expression .
Kochujang diets reduced hepatic glucose output and triacylglycerol accumulation and increased glycogen storage .
CONCLUSION : The combination of red pepper and fermented soybeans in kochujang improves glucose homeostasis by reducing insulin resistance , not by enhancing beta-cell function , in diabetic rats .
The improvement is associated with decreased hepatic fat storage by the activation of adenosine monophosphate kinase .
| Matching Sentences:
[ Sen. 6, subscore: 1.00 ]: Meju was produced by fermenting soybeans in a traditional method ( TMK ) or in a more modern method in which soybeans are inoculated with Bacillus subtilus and Aspergillus sojae ( MMK ) .
[ Sen. 7, subscore: 1.00 ]: RESULTS : TMK and MMK decreased body weight , visceral fat , and serum leptin levels without modulating caloric intake in diabetic rats compared with the control .
[ Sen. 8, subscore: 1.00 ]: TMK and MMK also improved glucose tolerance by enhancing insulin sensitivity but did not potentiate glucose-stimulated insulin secretion .
[ Sen. 9, subscore: 1.00 ]: The improvement in hepatic insulin sensitivity caused by TMK and MMK was explained by the potentiated phosphorylation of signal transducer and activator of transcription-3 --> adenosine monophosphate kinase --> acetyl-coenzyme A carboxylase and decreased phosphoenolpyruvate carboxykinase expression .
| | Supplemental links/files: reference in endnote online text related articles pubmed citation | |
Score: 3.00 |
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| Title: Cloning and characterization of ntTMK1 gene encoding a TMK1-homologous receptor-like kinase in tobacco | | Author: Cho HS Pai HS .
| | Journal: Mol .
Cells Citation: V : 10 ( 3 ) P : 317-24 Year: 2000 Type: ARTICLE | | Literature: oryza Field: abstract Doc ID: pub10901170 Accession (PMID): 10901170 | | Abstract: A cDNA encoding a receptor-like kinase , designated NtTMK1 , was isolated from Nicotiana tabacum .
The kinase domain of NtTMK1 contained all of 12 subdomains and invariant amino acid residues found in eukaryotic protein kinases .
The extracellular domain contained 11 leucine-rich repeats which have been implicated in protein-protein interactions .
The amino acid sequence of NtTMK1 exhibited high homology with those of TMK1 of Arabidopsis and TMK of rice in both kinase and extracellular domains , suggesting that NtTMK1 is a TMK homologue of tobacco The NtTMK1 transcripts were present in all major plant organs , but its level varied in different developmental stages in anthers and floral organs .
NtTMK1 mRNA accumulation in leaves was stimulated by CaCl2 , methyl jasmonate , wounding , fungal elicitors , chitins , and chitosan .
The NtTMK1 mRNA level also increased upon infection with tobacco mosaic virus .
| Matching Sentences:
[ Sen. 4, subscore: 3.00 ]: The amino acid sequence of NtTMK1 exhibited high homology with those of TMK1 of Arabidopsis and TMK of rice in both kinase and extracellular domains , suggesting that NtTMK1 is a TMK homologue of tobacco The NtTMK1 transcripts were present in all major plant organs , but its level varied in different developmental stages in anthers and floral organs .
| | Supplemental links/files: reference in endnote online text related articles pubmed citation | |
Score: 1.00 |
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| Title: Cloning and characterization of ntTMK1 gene encoding a TMK1-homologous receptor-like kinase in tobacco | | Author: Cho HS Pai HS .
| | Journal: Mol .
Cells Citation: V : 10 ( 3 ) P : 317-24 Year: 2000 Type: ARTICLE | | Literature: oryza Field: title Doc ID: pub10901170 Accession (PMID): 10901170 | | Abstract: A cDNA encoding a receptor-like kinase , designated NtTMK1 , was isolated from Nicotiana tabacum .
The kinase domain of NtTMK1 contained all of 12 subdomains and invariant amino acid residues found in eukaryotic protein kinases .
The extracellular domain contained 11 leucine-rich repeats which have been implicated in protein-protein interactions .
The amino acid sequence of NtTMK1 exhibited high homology with those of TMK1 of Arabidopsis and TMK of rice in both kinase and extracellular domains , suggesting that NtTMK1 is a TMK homologue of tobacco The NtTMK1 transcripts were present in all major plant organs , but its level varied in different developmental stages in anthers and floral organs .
NtTMK1 mRNA accumulation in leaves was stimulated by CaCl2 , methyl jasmonate , wounding , fungal elicitors , chitins , and chitosan .
The NtTMK1 mRNA level also increased upon infection with tobacco mosaic virus .
| Matching Sentences:
[ Sen. 1, subscore: 1.00 ]: Cloning and characterization of ntTMK1 gene encoding a TMK1-homologous receptor-like kinase in tobacco
| | Supplemental links/files: reference in endnote online text related articles pubmed citation | |
