Score: 1.00 | Title: Genetic and epigenetic alteration among three homoeologous genes of a class E MADS box gene in hexaploid wheat .
| Author: Shitsukawa N Tahira C Kassai K Hirabayashi C Shimizu T Takumi S Mochida K Kawaura K Ogihara Y Murai K | Journal: Plant Cell Citation: V : 19 P : 1723-37 Year: 2007 Type: MEDLINE | Literature: oryza Field: abstract Doc ID: pub17586655 Accession (PMID): 17586655 | Abstract: Bread wheat ( Triticum aestivum ) is a hexaploid species with A , B , and D ancestral genomes .
Most bread wheat genes are present in the genome as triplicated homoeologous genes ( homoeologs ) derived from the ancestral species .
Here , we report that both genetic and epigenetic alterations have occurred in the homoeologs of a wheat class E MADS box gene .
Two class E genes are identified in wheat , wheat SEPALLATA ( WSEP ) and wheat LEAFY HULL STERILE1 ( WLHS1 ) , which are homologs of Os MADS45 and Os MADS1 in rice ( Oryza sativa ) , respectively .
The three wheat homoeologs of WSEP showed similar genomic structures and expression profiles .
By contrast , the three homoeologs of WLHS1 showed genetic and epigenetic alterations .
The A genome WLHS1 homoeolog ( WLHS1-A ) had a structural alteration that contained a large novel sequence in place of the K domain sequence .
A yeast two-hybrid analysis and a transgenic experiment indicated that the WLHS1-A protein had no apparent function .
The B and D genome homoeologs , WLHS1-B and WLHS1-D , respectively , had an intact MADS box gene structure , but WLHS1-B was predominantly silenced by cytosine methylation .
Consequently , of the three WLHS1 homoeologs , only WLHS1-D functions in hexaploid wheat .
This is a situation where three homoeologs are differentially regulated by genetic and epigenetic mechanisms .
| Matching Sentences: [ Sen. 4, subscore: 1.00 ]: Two class E genes are identified in wheat , wheat SEPALLATA ( WSEP ) and wheat LEAFY HULL STERILE1 ( WLHS1 ) , which are homologs of Os MADS45 and Os MADS1 in rice ( Oryza sativa ) , respectively .
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