Score: 9.00 | Title: Divergent roles in Arabidopsis thaliana development and defense of two homologous genes , aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1 , encoding novel aminotransferases .
| Author: Song JT Lu H Greenberg JT .
| Journal: Plant Cell Citation: V : 16 ( 2 ) P : 353-66 Year: 2004 Type: ARTICLE | Literature: oryza Field: abstract Doc ID: pub14729919 Accession (PMID): 14729919 | Abstract: The disease-resistant Arabidopsis thaliana aberrant growth and death2 ( agd2-1 ) mutant has elevated levels of the defense signal salicylic acid ( SA ) , altered leaf morphology , and mild dwarfism .
AGD2 and its close homolog ALD1 ( for AGD2-LIKE DEFENSE RESPONSE PROTEIN1 ) encode aminotransferases that act on an overlapping set of amino acids in vitro .
However , kinetic parameters indicate that AGD2 and ALD1 may drive the aminotransferase reaction in opposite directions .
ALD1-deficient mutants have the opposite phenotypes from agd2-1 , showing reduced SA production and increased disease susceptibility .
Furthermore , ALD1 transcript levels are elevated in agd2-1 and are induced in the wild type by bacterial pathogen infection .
ALD1 is responsible for some of the elevated SA content and a majority of the disease resistance and dwarfism of agd2-1 .
A complete knockout of AGD2 renders embryos inviable .
We suggest that AGD2 synthesizes an important amino acid-derived molecule that promotes development and suppresses defenses , whereas ALD1 generates a related amino acid-derived molecule important for activating defense signaling . | Matching Sentences: [ Sen. 2, subscore: 2.00 ]: AGD2 and its close homolog ALD1 ( for AGD2-LIKE DEFENSE RESPONSE PROTEIN1 ) encode aminotransferases that act on an overlapping set of amino acids in vitro . [ Sen. 1, subscore: 1.00 ]: The disease-resistant Arabidopsis thaliana aberrant growth and death2 ( agd2-1 ) mutant has elevated levels of the defense signal salicylic acid ( SA ) , altered leaf morphology , and mild dwarfism . [ Sen. 3, subscore: 1.00 ]: However , kinetic parameters indicate that AGD2 and ALD1 may drive the aminotransferase reaction in opposite directions . [ Sen. 4, subscore: 1.00 ]: ALD1-deficient mutants have the opposite phenotypes from agd2-1 , showing reduced SA production and increased disease susceptibility . [ Sen. 5, subscore: 1.00 ]: Furthermore , ALD1 transcript levels are elevated in agd2-1 and are induced in the wild type by bacterial pathogen infection . [ Sen. 6, subscore: 1.00 ]: ALD1 is responsible for some of the elevated SA content and a majority of the disease resistance and dwarfism of agd2-1 . [ Sen. 7, subscore: 1.00 ]: A complete knockout of AGD2 renders embryos inviable . [ Sen. 8, subscore: 1.00 ]: We suggest that AGD2 synthesizes an important amino acid-derived molecule that promotes development and suppresses defenses , whereas ALD1 generates a related amino acid-derived molecule important for activating defense signaling .
| Supplemental links/files: reference in endnote online text related articles pubmed citation | |
Score: 1.00 | Title: Divergent roles in Arabidopsis thaliana development and defense of two homologous genes , aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1 , encoding novel aminotransferases .
| Author: Song JT Lu H Greenberg JT .
| Journal: Plant Cell Citation: V : 16 ( 2 ) P : 353-66 Year: 2004 Type: ARTICLE | Literature: oryza Field: title Doc ID: pub14729919 Accession (PMID): 14729919 | Abstract: The disease-resistant Arabidopsis thaliana aberrant growth and death2 ( agd2-1 ) mutant has elevated levels of the defense signal salicylic acid ( SA ) , altered leaf morphology , and mild dwarfism .
AGD2 and its close homolog ALD1 ( for AGD2-LIKE DEFENSE RESPONSE PROTEIN1 ) encode aminotransferases that act on an overlapping set of amino acids in vitro .
However , kinetic parameters indicate that AGD2 and ALD1 may drive the aminotransferase reaction in opposite directions .
ALD1-deficient mutants have the opposite phenotypes from agd2-1 , showing reduced SA production and increased disease susceptibility .
Furthermore , ALD1 transcript levels are elevated in agd2-1 and are induced in the wild type by bacterial pathogen infection .
ALD1 is responsible for some of the elevated SA content and a majority of the disease resistance and dwarfism of agd2-1 .
A complete knockout of AGD2 renders embryos inviable .
We suggest that AGD2 synthesizes an important amino acid-derived molecule that promotes development and suppresses defenses , whereas ALD1 generates a related amino acid-derived molecule important for activating defense signaling . | Matching Sentences: [ Sen. 1, subscore: 1.00 ]: Divergent roles in Arabidopsis thaliana development and defense of two homologous genes , aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1 , encoding novel aminotransferases .
| Supplemental links/files: reference in endnote online text related articles pubmed citation | |